What Are Mast Cells?

by Dr. John Gannage | Dec 29, 2016 | Blog, General Wellness, Histamine

This post is part of an ongoing series on histamine intolerance, which Dr. Gannage has described as a “game changer in chronic illness”. If you missed the first post, which explains what histamine intolerance is, you can read it here. Histamine is released...

Heavy Metals, Mast Cell Activation, and Histamine Intolerance

by Dr. John Gannage | Jan 12, 2021 | Blog, Detoxification, Heavy Metal Toxicity, Histamine, Integrative Medicine

This article explains how over-exposure to heavy metals can contribute to dysfunction in mast cell activation, which in turn impacts histamine levels in the body.  Overview of Mast Cells If you struggle with health issues related to histamine intolerance and would...

DAO: Overview and Role in Histamine Intolerance

by Dr. John Gannage | Feb 24, 2021 | Blog, Enzyme Deficiency, Gut Health, Histamine, Integrative Medicine

Histamine is a naturally occurring chemical that is involved in several physical functions, including allergic and inflammatory reactions. It is also found to varying degrees in food and drinks. In histamine intolerance, there is an imbalance between levels of...

7 Surprising Factors that Can Increase Histamine Levels (And How to Deal With Them)

by Dr. John Gannage | Nov 17, 2020 | Blog, Gut Health, Histamine, Integrative Medicine

There are a number of surprising factors that can increase histamine levels. Read on to find out more. Histamine intolerance is a condition that is generally managed with diet and lifestyle changes. The most well-known of these may be the low histamine diet, in which...

Part 1: The 3 W’s of Postural Orthostatic Tachycardia Syndrome (POTS)

by Dr. John Gannage | Aug 18, 2020 | Blog

Our nervous system is astoundingly complex. It coordinates our movements and sensory information by sending signals to and from the brain to different parts of the body in less than a second. It is made up of the brain, spinal cord, and numerous neural networks...

The Low Histamine Diet

by Dr. John Gannage | Jun 6, 2020 | Blog, Histamine, Nutrition

What is Histamine?  Histamine is an organic compound that is both naturally occurring in our bodies and found in many of the foods we eat. It serves us a variety of purposes, from acting as a neurotransmitter in the brain to regulating gut functioning. We require it...

Spotlight on Vitamin C

by Dr. John Gannage | Apr 30, 2020 | Blog, General Wellness, Histamine, Nutrition

Vitamins are an integral component of our health and longevity. Their function in biochemical and physiological processes helps ensure we maintain energy, protection from illness, and well-being throughout our lifetime.  Since the emergence of COVID-19, the...

Fundamentals of Functional Medicine: Understanding Inflammation

by Dr. John Gannage | Dec 13, 2019 | Blog, Featured, General Wellness, Integrative Medicine, Nutrition

The Fundamentals of Functional Medicine series is intended to be an overview of the common elements and underlying imbalances behind chronic illness of all kinds, including inflammation, oxidative stress, mitochondrial dysfunction, and gut dysbiosis. The Problem:...

Histamine Intolerance and the Gut: A Web of Connections

by Dr. John Gannage | Nov 11, 2019 | Blog, Featured, Histamine

Histamine Intolerance and the Gut: A Web of Connections  Histamine intolerance and the gut are interconnected in many ways. The root cause of histamine intolerance can often be traced back to an issue or imbalance in the gut, including SIBO, dysbiosis, leaky gut, or a...